|
KMID : 1059520090530040422
|
|
Journal of the Korean Chemical Society
2009 Volume.53 No. 4 p.422 ~ p.426
|
|
|
Practical and Green Approach for N-Boc Protection of Amines Catalyzed by Indion 190 Resin
|
|
Chaskar Atul
Yewale Sampat
Langi Bhushan
Deokar Hrushikesh
|
|
|
Abstract
|
|
|
|
An efficient, chemoselective and practical protocol for N-Boc protection of amines using di-tertbutoxypyrocarbonate (Boc)2O in presence of Indion 190 resin. Resin was easily separated from the reaction mixture by filtration and reused in subsequent reactions without any apparent loss of activity. Simple workup, mild condition, short reaction time and high yield are some of the striking features of the present process.
|
|
|
KEYWORD
|
|
|
Amines, Indion 190 resin, Di-tert-butoxypyrocarbonate (Boc)2O, Chemoselectivity
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|